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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49e844996a9ae84d411fca090a1305c18cbcfa03e72a8d83b983e29387f7cc42' 
  AND token = '3GJcf+87iQQwf+UL7/8QRJ0/oictzrrkZz7pSIxFaqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}