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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05f9fae205b31b5e0d13e72cd38cc15134e6cbaca75a2afbe43c6800773f114d' 
  AND token = 'Cs9e4qctNXwoeFhV7u1U16PMzZ6OG2qZTcTc9ipDJNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}