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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '269ae36dc86fa4d6e458916e46a2841b84703faae70c195203703d0d4649b527' 
  AND token = 'Rm5DEkA3jykFpc1gCpJfzBNyCmoyEb6h7mzPu+PbLAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}