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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8a52590cb9b1e4b22dc235454d61b3a71578f827c2bbb0f231d3dc3db12acc9' 
  AND token = 'ojGjJKjcXqdIl0nSxaViFJdxnNM+lFLUJRBpi8ulB4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}