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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea9d9c9e1ca66a0faef4556bf8c069fd750af7f26c3175558ef293edb91f1ae0' 
  AND token = 'm8EQeNT59y5IVYt1gKeqeGnFd8wF/B6GBU6mgQrZHuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}