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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e2e493152e42c333bbad5045a8327e462eb80a1da086eebc6d74812f85221d' 
  AND token = 'FBvmPoLd7rDv0GhS4Hxv8upu9AkFf3WxHMsCzxZFFQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}