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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b1c9c6c7d0243237650ec97123c107b3fa6ed980e02f97d55de30e8f0e08373' 
  AND token = 'fAyi/G1g9HqN5mXIr4AAm4PCNO+H7VC0WViIOM/QFPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}