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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d4d0df7174d148df5889de949a862ddb2eee4ea5f497958f666231c2c6aa1f9' 
  AND token = '/ihMU+C2yxEofOCGM/n4mQoNq4NgEvGrrmY1TAg+stE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}