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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a647ce45835dc0228fe4d5034c5eb640574e6f29b36934a804c25c480a621ba1' 
  AND token = 'LmOtONTUTQV+ddx2641vKeLpIFwh71o37UcbZKSFEu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}