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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '490dff01cc3b801de8d488125d6de11a89e9b92133bfbecd9ce010bef6d7e391' 
  AND token = 'oZst6H/5c0D+duiiw/Yn6V7p3Pp5JwKxkC+RIyfsWHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}