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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b41b3b466519bb7c433d79420bb9183682b4183fd4b3b767202741c6ca4a8a6' 
  AND token = '/iTS48JebXDv6jiNTGDZ12VywH5NwaSG/1cVbfD/dtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}