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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59e0ae53ea111ab1156b9ad9c76d543ccafb8a31d76be0de10972e3be3d030ec' 
  AND token = 'F5rrOaLfEKCk+NH0KhCVyBwV/IU5fzH3cMOb75AzrmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}