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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d2e66c0eb208acf4beabb7281329ce0bd93a7ab9f99a3db6ef6bb73749c7c7a' 
  AND token = 'iAp1h0NeWJL0LRcm+XyHUPyho1FCj5vpp25gLeW6KME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}