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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7df40b89ad8b870a953a3d121600d946787bd2c14d85eae6d4337aa903abc75e' 
  AND token = 'Y5A+S+cQEC9Xcz3c/0nYx6671UBVQq5IuIVemDT/0zE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}