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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9339485c3eac039e70520ed980b3c8c736fef3c9defb7656e892c978737cb88e' 
  AND token = 'rqROQwDaCF2s0heEPveZeh4745a/nTci+mdMRok/4tw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}