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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43a0edbeeeb5f4e46f9487c2e09f78ac04b9bd74f276fc3a3dd8749e9b6e91e9' 
  AND token = 'rjuOySo+t/ayIl/3I3CYXWrNNTOvkN7d1Bv9SvZ+P+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}