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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ae40b4b2c034dc05829795605f80e8edd85625b59ac8e881f789011aeb82623' 
  AND token = 'HuMm7Oh4Z+saE9BHUCgxOiq3LzuQTPcTI/bqNasBFDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}