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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11dcc3af19abc2aba7d88ab2c3502f087c594e3b4db8a79ebd0b7bf6a8c04d36' 
  AND token = 'WF5JARkZtd4eyGYp7XeGDM5WxAaIVbZ6MFNlgG/GQwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}