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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '550afe205646d5560d08a7a2c634db26b3d98dd449e1cac1fe01bd5e733ae3ec' 
  AND token = 'VEy5zUxplwkeimDtvyMnRSKnMZ0T5pnTqGu0UScgsLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}