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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5879b7a4c13c118e47b337d55a4eec775291a42d99c3ed55a81a00de6e9dcba5' 
  AND token = 'BGh+0/J99nS1ObuS7gPuzgCs9A7jNp5v49ZJnQikA1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}