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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22eb1e60abb9fb963d9a56b953cafbfd2847b95bdecf07c4ea28410ac7094461' 
  AND token = 'BbF/RacC+jk47xI8e50dahi+sgYWIRfWuV7XzPK+WxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}