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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef4da9d7a2dff221185ddb04a468cc2d3c45acfeea179edcddd16d93421c441d' 
  AND token = 'vGEs1JCwMnYcFRorZ4FSb4zvplCCv3L/KX/iX+tyCCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}