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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2c8dd4107a5ee80aabc5892f5d3162223c9eca981cfbed99df48a3cdceec35d' 
  AND token = 'YJb1DGIvRb/4WPsDJi8b9LEKM652o/+POjvTvlGM2No=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}