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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '665585e4ce18bd8337920117d0560e0f430480fec797f0438398bc218c747635' 
  AND token = 'Ffb3jus4qUvKoE8FiEEqxoV+dwkKMnNaS4HJBftvmFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}