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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a490bcd51a1c852403f06d7247fc58bc6af90739e5308ee638c8385c53a5e7f' 
  AND token = 'xvgOGG+PVab5lorfFBcTucBuxU/9+uT9+jYLk1Gpgm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}