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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0306ad5b68bf807ed61a1327067d17ab999c737e5e0e16594ae9258934b9024f' 
  AND token = '3z7TEfVxlS5R825lBr6UbpZlxsFM9bSQDcDtMo4QVeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}