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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '219564a2e118d2114811375d44486d5db08ab7425408612eb6d2d8c1c0bda40a' 
  AND token = 'zAkPvj2SIUhuhOeyqaok9BedY7v/B1RcZBkgK6tQVD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}