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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b74484ebdf079a2b329abc7f739933fc90b0e38e660c2d0cdbe3932af610e2a' 
  AND token = '4yDdsancJ37IdM05mGUPLr+cKYKzAO92nbVq8D/h2mY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}