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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b16d2678733221417558034c1dae08dd46eef40a69b6d3f7e653946695b28ac' 
  AND token = 't1gA3iEMichMuR+q57TqV+y0znvYaW+38Q6GDs2ZPmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}