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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db8c697a616542190748f43eb3d0fac13783386a017186d0d22a616838f6ede9' 
  AND token = 'JX2XZsY2rdSo1VgFFDiHWoq54lCSOf3SMbFyPyxCPvw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}