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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '953fddaa3d1bd2d1e3fba3f36f97f30a936e508da8868fc1e4699d6a97e3e3b4' 
  AND token = '11/X1eFktvoG9zqQl3OxTB6BJ8IodvWaNy7Q8uVVqM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}