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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53807ee49c3d6f4ba5ce2789a6379f88bb41b2455a25f87de2f8025033dcaa4f' 
  AND token = 'rkU7wQbPDPNlEq/17VbXb1c7eRadtGfmfc7M7hImBiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}