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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3757d6afc43cd06c41850ce4ed0aef23c98359c495390d8da259796edc3cff2e' 
  AND token = 'UuOJiujgkkbdRslZnNmvWkUBQ2VsS1hjRwiZJatmMic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}