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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee42cf4db4bb27d053e94b354026d265ec6923cb50636f6c0910a01b16d9f37f' 
  AND token = 'GVPd4GgAFoVAFp+TOkxPJ/RBgoXtjQMjgl2ILVF0RUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}