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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e9f6c1844fb40d059462fb75f7c3b7f7af250b33b9239b08a86731132fc4c99' 
  AND token = '9NRC9mwUgyxkObdxqHM0W68BJaaDsCE7JLy96bZGf1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}