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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4f90a7361c07137577447709769fcfdbf587eb5a1a36982495dfb615c9cc5fe' 
  AND token = 'q8mQbE3nMPGRYF9bgwDg1wWOo3ciZjuSBeL4IDBGWLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}