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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '778dd3476d2bac9782b846d1b6ee75dda6b4caa531d6f8e11ed2444b305bbc00' 
  AND token = '0PlYw68pwn8+xmcRyQ/07qup9H4iu7BAqdr0K19o2Yc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}