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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c0227bbf1c1c712b5aaedab6ae386840f6628c1f9c7977cc55ca484bb2c5267' 
  AND token = '44E2JE7uDN3+LcQJo9RJyQ9cvhNq0IFzuIcaOPfOuTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}