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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5e0d6b9c37cafd938fb7a4c2ad3834edb45fa876b5af7b7839233a0ce515807' 
  AND token = 'UPw25HBHKaPFl/yGHa0QfD6voJZlA5oiEwH4mP/y99M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}