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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff22d02dd55910ff1f974bed0cbc9da2c1641b123ba677427bd905aa8cbf8f25' 
  AND token = '4V3E2LQDPp1xdtGhwhipEE+poGIYdLw4VOnryP49I+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}