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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e012aaef13fa7df00691281282d4cb2a52e6d516272c5f8e495a9a3e50282df' 
  AND token = 'vy3I0ovYtkezbDLz5dKe6VIfj9ByeslZ7D0OBlptgzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}