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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3224f329a265893f1c2ac09fb00fb3a985d026fb71be4c5551dfb1e09115f5d0' 
  AND token = 'Oq+9TYdb2nJBcTMO94w+24nZFe1qpjtolZPZjp1a/NI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}