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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05201d38466cec41f0cd8bdd851a0eda7a23adee91fbee47255584fd889e4cf1' 
  AND token = 'HhckctAjHeZmjEjF0i0yXX+8v7hHywFk8+g4AA1pAeM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}