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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1943f8bc791763162ef1da0855b4fc5f59e216775d31f5aed866d203c65d2ab2' 
  AND token = '+QEDMQdzqsKT5k9nsB+U1NYubc/h7w9abD09WSLhywQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}