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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6317881c4e44bf657d5c7df834ab2e229725f865b910028208ce1e4d9ed92195' 
  AND token = 'ZSHkdKW1FdBuNUkAaeNsznxcyE604JbQxZ7MWR0ir2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}