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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71eb80254b6e7fd77e1154940c23edc8b780c0b75538218991da1550fad9e205' 
  AND token = 'y9xhWS7Z9u1M/reCXMKpQnmPCkzGY9GdScLa5HfoOjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}