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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e9d8e172e1aa71c4d831fb3fb3594fe6b412a458b47a0136711cd0e103e343b' 
  AND token = 'bGx4oT47DYnvv/RK41pQr9f/n9FAkXA0pIbLllFua8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}