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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f83b67ed4a835ff8449bef48e30294fef5e1141620a285f735d02f7fc79c2b0' 
  AND token = 'xskn72dTzBK+JHXjNUHxWszTadi5PW83aJNxQo+Hbjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}