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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8db65a9b7f68f87794f1bdd5210b8521adc1989aa81e8c4a2d47389951d8395b' 
  AND token = '2CbFHsA0PuHjrGbxpa/taMcr05uGWwIX5P9NJQpBUqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}