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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc9641be521b5bf3fcadbe05dd632805b9c6c81f24c7d089b77009ede17969f4' 
  AND token = '1HKIuzWSW89XWcBVGIRdOMWd+/pkypIWkB8Pec9pQy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}